Floral biology and pollination ecology of Desmos chinensis (Annonaceae): assessing the efficacy of floral synchrony for promoting xenogamy

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Time-dependent trapping of pollinators driven by the alignment of floral phenology with insect circadian rhythms

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Reproductive resource partitioning in two sympatric Goniothalamus species (Annonaceae) from Borneo: floral biology, pollinator trapping and plant breeding system

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Generalized camera calibration model for trapezoidal patterns on the road

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The evolution of unisexual flowers in the Annonaceae: evidence from Pseuduvaria mulgraveana

Insect-Plant evolutionary ecology (Session I)The early-divergent angiosperm family Annonaceae has predominantly hermaphroditic flowers, although unisexuality has evolved in several disparate lineages. Pseuduvaria, an Asian-Pacific distributed genus with 57 species has largely unisexual flowers. A recent monograph of this genus reported that many species have both staminate and structurally hermaphroditic flowers; the latter were previously considered to be functionally pistillate, with stamens that produce small, irregular pollen that was likely to be sterile. We investigated the viability of the freshly-...postprin

Real-Time Estimation of Lane-to-Lane Turning Flows at Isolated Signalized Junctions

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Evolution of pollinator traps in Goniothalamus and Dasymaschalon flowers (Annonaceae), associated with short floral receptive periods

Oral Session: Species interactionsAnnonaceae flowers are protogynous and mostly have loosely enclosed pollination chambers that are often associated with beetle pollination. Unlike many other species having a receptive period of several days, field studies of the genera Goniothalamus, Dasymaschalon and Desmos reveal that they have short receptive periods of 23–26 hours. Trapping mechanisms have evolved independently in Goniothalamus and Dasymaschalon. Beetles are unable to leave the flowers until the end of staminate phase, which coincides with the onset of the pistillate phase of other flowers. Desmos chinensis, which is closely related to Dasymaschalon and which also has a short receptive period, does not show an equivalent …postprin

Identification of serum miR-139-3p as a non-invasive biomarker for colorectal cancer

Aberrant levels of circulating microRNAs are potential biomarkers for the early detection of colorectal cancer. The aim of this study was to study miR-139-3p and miR-622 in serum as a non-invasive biomarker for colorectal cancer diagnosis. We applied quantitative polymerase chain reaction to determine the levels of miR-139-3p and miR-622 in 42 pairs of tumor and adjacent non-tumor tissues, and in serum samples of 117 patients and 90 control subjects. Our results showed that miR-139-3p was silenced whereas miR-622 was overexpressed in colorectal cancer. Similarly, serum miR-139-3p level was significantly lower in colorectal cancer patients than in control subjects whereas miR-622 was more frequently detectable in patients. ROC analysis showed that AUC of miR-139-3p was 0.9935, with a sensitivity of 96.6% and specificity of 97.8%. Serum miR-139-3p level showed high sensitivity and specificity for both early and late stage CRCs and proximal and distal CRCs. Detectable serum miR-622 showed a sensitivity of 87.5% and specificity of 63.5% for discriminating CRC patients, but the sensitivity dropped for late stage patients (72.7%). We also included analyses of the blood CEA level for comparing the diagnostic performance of these blood-based biomarkers. The median level in CRC patients (3.6 ng/ml) was significantly higher than that in control (1.8 ng/ml). The AUC value of CEA in diagnosing CRC patients was 0.7515. CEA showed a positive correlation with tumor stage and age of patients and its level was higher in male. Collectively, serum miR-139-3p has strong potential as a promising non-invasive biomarker in colorectal cancer detection.published_or_final_versio

Identification of serum miR-139-3p as a non-invasive biomarker for colorectal cancer

Aberrant levels of circulating microRNAs are potential biomarkers for the early detection of colorectal cancer. The aim of this study was to study miR-139-3p and miR-622 in serum as a non-invasive biomarker for colorectal cancer diagnosis. We applied quantitative polymerase chain reaction to determine the levels of miR-139-3p and miR-622 in 42 pairs of tumor and adjacent non-tumor tissues, and in serum samples of 117 patients and 90 control subjects. Our results showed that miR-139-3p was silenced whereas miR-622 was overexpressed in colorectal cancer. Similarly, serum miR-139-3p level was significantly lower in colorectal cancer patients than in control subjects whereas miR-622 was more frequently detectable in patients. ROC analysis showed that AUC of miR-139-3p was 0.9935, with a sensitivity of 96.6% and specificity of 97.8%. Serum miR-139-3p level showed high sensitivity and specificity for both early and late stage CRCs and proximal and distal CRCs. Detectable serum miR-622 showed a sensitivity of 87.5% and specificity of 63.5% for discriminating CRC patients, but the sensitivity dropped for late stage patients (72.7%). We also included analyses of the blood CEA level for comparing the diagnostic performance of these blood-based biomarkers. The median level in CRC patients (3.6 ng/ml) was significantly higher than that in control (1.8 ng/ml). The AUC value of CEA in diagnosing CRC patients was 0.7515. CEA showed a positive correlation with tumor stage and age of patients and its level was higher in male. Collectively, serum miR-139-3p has strong potential as a promising non-invasive biomarker in colorectal cancer detection.published_or_final_versio

Identification of microRNA 885-5p as a novel regulator of tumor metastasis by targeting CPEB2 in colorectal cancer

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